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Tackling PFAS contamination with cutting-edge robust analytical solutions

Shimadzu Corporation
12 Nov 2024
Carrie Haslam
Associate Editor
Tackling PFAS contamination

Per- and polyfluoroalkyl substances (PFAS) are a diverse group of over 4000 organic fluorinated compounds, which have been widely used in industry since the 1950s. Their properties make these substances heat-resistant, oil- and water-repellent, and chemically and thermally stable.

For these reasons, PFAS have multiple uses and commonly function as surface treatment agents, water repellents, coatings and even fire extinguishers. Those very properties make them resistant to degradation and this has led to their persistence in the environment and bioaccumulation through food chains and other routes of exposure.

In this expert guide, we explore Shimadzu Corporation’s range of chromatography and mass spectrometry (MS) solutions for detecting very low levels of PFAS in a range of matrices. Plus, learn through a series of case studies how Shimadzu’s Triple Quadrupole LCMS instruments and other analytical methods meet and often exceed performance criteria included in EPA methods for PFAS analysis – generating accurate results with fast turnaround times designed to enhance lab productivity.

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The LCMS-9050 is a Q-TOF mass spectrometer designed for the most reliable and easy acquisition of accurate masses in real laboratory settings. The proprietary innovation for fast polarity switching has the unique capability for high-confidence identification of challenging compounds and high-throughput screening of multiple unknowns.  

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Prominence Ion Chromatograph

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The Prominence Ion Chromatograph with built-in electrodialytic suppressor boasts the same low carryover and excellent injection precision characteristics of Shimadzu HPLCs to bring you highly reliable results. 

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LCMS-TQ RX Series

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The LCMS-TQ RX series (LCMS-8060RX, LCMS-8050RX, and LCMS-8045RX) triple quadrupole high-performance liquid chromatograph mass spectrometers provide higher sensitivity, stability, and convenient operability.

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Ion ChromatographyIon chromatography, also known as ion exchange chromatography, is a high-performance liquid chromatographic technique used for the separation and identification of ions or polar molecules in a sample, including proteins, nucleotides and amino acids. Equipment includes ion exchange columns, ion exclusion columns, ion chromatography systems, pumps, and detectors. Find the best ion chromatography equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.LC-MSLC-MS (liquid chromatography-mass spectrometry) systems and equipment are used for separation and quantitative analysis of complex mixtures, combining liquid chromatography and mass spectrometry. Quantify proteins, contaminants, pesticides or screen for drug metabolites with a high level of sensitivity. LC-MS systems and equipment include reverse phase, normal phase and specialized columns integrated with various MS detectors such as time-of-flight (TOF), quadrupole, orbitrap or ion trap mass analyzers. LC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzer give greater sensitivity and resolving power to your analysis. Find the best LC-MS equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Mass SpectrometryMass spectrometry (MS) is a powerful analytical technique used to identify and quantify molecules based on the mass-to-charge ratio of gas-phase ions. It provides detailed information about the structure, composition, and properties of compounds and is widely used across fields such as environmental monitoring, materials science, drug discovery and development, food and beverage testing, and wider chemical research. Key MS techniques include tandem mass spectrometry (MS/MS), liquid chromatography–mass spectrometry (LS-MS) and inductively coupled plasma (ICP-MS). Choosing from these wide range of techniques and technologies can be a daunting task, so keep up to date with scientific applications, performance expectations, and customer reviews here all in one place. Visit our product directory to receive quotes direct from the manufacturer. PFASDetection LimitsToxicityToxicity is defined as the degree to which a substance can harm humans or animals. It is essential to study the toxicity of pharmaceutical products during the development process so that optimum dosage can be established for the administration of the drug.ChromatographyChromatography is a powerful technique used to separate and analyze components of mixtures based on their chemical properties. It is widely used in fields like biochemistry, pharmaceuticals, and environmental analysis. By exploiting differences in the interaction of substances with a stationary phase and a mobile phase, chromatography enables precise purification and quantification of compounds. Whether you're working with complex biological samples or industrial chemicals, chromatography is essential for obtaining high-quality results. Browse our peer-reviewed product directory to find the best chromatography systems, compare products, read customer reviews, and get pricing directly from manufacturers.LC-MS / MS

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