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Superior Ointments: What’s the Strategy?

24 Apr 2014

This white paper describes methods suitable for analyzing the physical properties and spreading behavior of ointments.

Wells/Brookfield™ Cone & Plate

AMETEK Brookfield

The Wells-Brookfield Cone/Plate Viscometer/Rheometer gives researchers a sophisticated instrument for routinely determining absolute viscosity of fluids in small sample volumes. Its cone and plate geometry provides the precision necessary for development of complete rheological data.The Wells-Brookfield Cone/Plate Viscometer/Rheometer is a precise torque meter which is driven at discrete rotational speeds. The torque measuring system, which consists of a calibrated beryllium-copper spring connecting the drive mechanism to a rotating cone, senses the resistance to rotation caused by the presence of sample fluid between the cone and a stationary flat plate.The Wells-Brookfield Cone/Plate Viscometer/Rheometer provides a wide variety of shear rates and viscosity ranges, which can be further extended by the use of interchangeable cone spindles. Different models can be selected to meet the specific range of viscosities and shear rates required.Wells/Brookfield™ Cone & Plate Features and Benefits Determine absolute viscosity of small samples (0.5 - 2.0 mL) Precise shear rates for determining a material's flow curve behavior Rapid temperature control due to small sample size Electronic gap adjustment for simplified setup and increased throughput Touch Screen Display available on DV3T Rheometers and DV2T Viscometers Auto-zero function to ensure precision torque measurement Auto-range function to define full scale range (FSR) for all spindle/speed combinations Torque measurement accuracy: 1% of full scale range Repeatability: 0.2% of full scale range

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RheometryRheometers are used to measure the rheology of fluids, which is the flow of fluids in response to an applied force. The most common types of rheometer include shear rheometers (capillary, cone and plate and rotational cylinder) and extensional rheometers. Viscometers are similar to rheometers however viscometers only measure the viscosity of a fluid.Particle CharacterizationParticle characterization instruments are used to determine particle size distribution, shape, surface area, zeta potential, density and porosity of particles and materials. Multiple tecchniques are available for determining particle size, shape and count including dynamic light scattering (DLS), laser diffraction, electrozone (Coulter technique), imaging particle analysis and single particle optical sensing. Determine the density of your material with a gas pycnometer or examine its surface area and porosity with gas adsorption analyzers and mercury porosimeters. Find the best particle characterization instruments in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Drug DeliveryDrug Delivery refers to dosage form, route of administration, formulations, technologies, and systems for transporting a pharmaceutical compound in the body as needed to safely achieve its desired therapeutic effect. Drug delivery is often approached via the biopharmaceutical or small molecule drug's formulation, but it may also involve medical devices or drug-device combination products. Considerations include instrumentation, software and services. RheologyPharmaceuticalsPharmaceuticals are medicinal drugs used in healthcare to diagnose, prevent, cure and treat illnesses. Pharmaceuticals that are excreted after use appear in wastewater and can have detrimental effects on the environment.
Superior Ointments: What’s the Strategy?