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Supercritical fluid chromatography FAQs

11 Oct 2024

Research on supercritical fluid chromatography (SFC) as an analytical technique began in the 1960s. Typically, SFC refers to chromatographic technique involving using supercritical carbon dioxide as the mobile phase. Explore these FAQs for a thorough break down of some of the most common questions when working with SFC.

Prominence Ion Chromatograph

Shimadzu Corporation

The Prominence Ion Chromatograph with built-in electrodialytic suppressor boasts the same low carryover and excellent injection precision characteristics of Shimadzu HPLCs to bring you highly reliable results. 

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Supercritical Fluid ChromatographySupercritical Fluid Chromatography (SFC) is used for the rapid separation and analysis of complex mixtures. SFC systems require injectors, pumps, columns, ovens and detectors. The SFC retention method uses a supercritical fluid, usually CO2. There are a number of different SFC detector types including UV / VIs, ECD, mass spectrometry and fluorescence.PurificationPurification techniques are essential for isolating compounds of interest from complex mixtures, such as proteins, nucleic acids, and chemicals. These techniques are critical in biochemistry, drug development, and environmental studies. Explore purification systems in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.Sample IdentificationBio-Separations