Studying fibroblast activation and production of extracellular matrix proteins with RASTRUM 3D cell models

16 Nov 2023

In this application note from Inventia, explore the creation of 3D cell models using normal human lung fibroblasts (NHLF) and liver stellate cells (LX-2) printed in RASTRUM™ Matrix. Furthermore, discover how the data collected demonstrates that RASTRUM can generate 3D fibroblast models that can be used in phenotypic screening and other applications.

RASTRUM™

Inventia

RASTRUM™ is a 3D cell culture platform that enables scientists to generate biologically and phenotypically relevant models for disease research, drug discovery, and translational applications with greater efficiency and consistency.

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Cell / Tissue CultureCell culture or tissue culture is used to study the biology of cells or tissues and to isolate cellular products in an environment which can be manipulated and well defined. Accurately control your culture environment with bioreactors or culture incubators, bind your cells to a surface or together with an extracellular matrix. Distinguish cell types with differential media or proliferate cells with certain characteristics using selective media. Enrich your media with supplements such as growth factors, sera and vitamins. Find the best cell and tissue culture products, kits and equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Phenotypic ScreeningPhenotypic screening assesses cellular responses to compounds, enabling drug discovery and target identification. This technique is pivotal in finding effective treatments for complex diseases. Discover phenotypic screening platforms and tools with peer-reviewed comparisons and pricing in our directory.
Studying fibroblast activation and production of extracellular matrix proteins with RASTRUM 3D cell models