ResourceLife Sciences
Streamlined Spheroid Based Drug Screening Luminescent Assay
27 Mar 2018In this application note, spheroids are generated in PrimeSurface ULA plates, the cell viability of 4 different tumor cells and use of intracellular ATP measurement CellTiter Glo® (Promega Co., Ltd) for luminescent assay screening are demonstrated.
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PrimeSurface® 3D culture: White, Ultra-low Attachment Plates: 96 well, U bottom plates
PHC Corporation of North AmericaGrow Uniform Spheroids with Ultra-low Attachment PrimeSurface® Cell Culture Plate
PrimeSurface® 3D culture: White Ultra-low Attachment Plates: 384 well, U bottom plates
PHC Corporation of North AmericaGrow Uniform Spheroids with Ultra-low Attachment PrimeSurface® Cell Culture Plate
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Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.SpheroidsSpheroids are clusters of cells that have been grown in 3D culture to be used as <i>in vitro</i> model systems. These 3D microtissues can be used for toxicology testing, DMPK studies and many other applications involving cell analysis.ScreeningUsing robotics, data processing and control software, liquid handling devices and sensitive detectors, screening allows a researcher to quickly conduct millions of chemical, genetic or pharmacological tests.TumorsTumor research focuses on understanding abnormal cell growth that leads to cancer. Identifying biomarkers, studying tumor microenvironments, and developing targeted therapies are critical for advancing cancer treatment. Early detection and personalized treatment options are key to improving outcomes for patients. Browse our peer-reviewed product directory to explore tools for tumor research, diagnostics, and cancer therapies; compare products, read customer reviews, and get pricing directly from manufacturers.LuminescenceLuminescence techniques detect and measure light emitted by substances during chemical reactions or biological processes. Widely used in assays for diagnostics, environmental monitoring, and drug screening, luminescence-based methods offer high sensitivity. Explore leading systems and products in our directory.