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Split Injections in Gas Chromatography: How to Reduce Inlet Discrimination by Using a Liner with Glass Wool

Phenomenex Inc
12 Apr 2016

In this application note Phenomenex describe the use of a liner containing glass wool to reduce inlet discrimination when making a split injection, ensuring a more accurate analysis. A comparison of two different liners is shown – one with a single taper liner and one which also contains glass wool, this provides additional surface area for volatilization.

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Zebron™ ZB-XLB GC Columns

Phenomenex Inc

Zebron ™ ZB-XLB-HT is a phenyl-si-arylene bonded phase that can withstand temperatures up to 400˚ C, enabling analyses of compounds with high molecular weights and boiling points. The Zebron Inferno non-metal columns are stable at high temperatures due to proprietary coating and binding technologies, providing long lifetime, low bleed and low activity. They are ideal for analyses in environmental, food and beverage, pharmaceutical, toxicology and biofuels applications. The ZB-XLB-HT Inferno provides unique selectivity for confirmational analyses. This MS-certified column offers low activity and good peak shape for acidic and basic samples. It is also ideal for polychlorinated biphenyls (PCBs), pesticides, herbicides and many EPA methods.Non-metal si-arylene GC column stable to 400 ˚CRobust column for high temperature analysisProvides unique selectivity for conformational analysesLonger lifetime with high temperature, polyimide coated, fused silica tubingGood tool for general screening to identify unknown samples Resolve Complex Samples Without Sacrificing Sensitivity

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Ultra Inert Liners

Agilent Technologies

Agilent’s Ultra Inert Inlet Liners prevent adsorption and ensure accurate sample transfer onto the GC column through a robust deactivated surface. These liners are recommended for trace level analysis of active analytes. Liners with inert wool retain non-volatiles, prolonging column life and lowering frequency of MS source maintenance.

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Split Injections in Gas Chromatography: How to Reduce Inlet Discrimination by Using a Liner with Glass Wool