Selecting a Reversed-Phase Column for the Peptide Mapping Analysis of a Biotherapeutic Protein

27 Nov 2017

A chromatographic peptide mapping method must provide adequate resolution and recovery of a broad set of peptides if it is to be used in the quality analysis of a biotherapeutic protein. In this application note, a range of reversed phase columns by Waters are analysed for their applicability to peptide mapping, demonstrating high peak capacity separations.

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