Screening Method for 122 Acidic, Neutral and Basic Drug Analytes in Plasma, Serum, Urine, or Tissue by LC-MS/MS
13 Feb 2015With the use of LC/MS/MS and full screen (QTrap methodology) the complete detection of both illicit and prescribed drugs can be accomplished easily with a simple solid phase extraction preparation. This application note shows the development of a rapid, highly sensitive qualitative method for the analysis of acidic, neutral, and basic compounds in biological fluids using Clean Screen XCEL® I solid phase extraction columns. The sample preparation is minimized while efficiently extracting a large group of representative compounds.
Related Products
Request Quote for All Products
Clean Screen® XCEL Solid Phase Extraction Columns
UCT, Inc.The Clean Screen® XCEL Solid Phase Extraction Columns are a line of sample prep phases designed to reduce the number of steps in the extraction, and therefore the amount of time and solvent necessary to complete the sample cleanup. Further advantages include reduced sample size and improved cleanliness and recovery. The Xcel I column will extract a wide array of basic drugs including benzodiazepines and opiates. The Xcel II column is designed solely for the extraction of the THC metabolite.