ResourceSpectroscopy

Rapid infrared microscopy in pharmaceutical product development, quality control and biologics formulation

12 Dec 2023

In this application note, Thermo Fisher Scientific emphasizes the critical role of Fourier transform infrared (FTIR) microscopy in providing essential data for pharmaceutical companies. The focus is on the varied applications of FTIR microscopy in the pharmaceutical industry, including reverse engineering of solid dosage forms, verifying composition in quality control laboratories, understanding batch-to-batch variation, identifying foreign particulates, and detecting counterfeit pharmaceuticals. The note highlights the Thermo Scientific™ Nicolet™ RaptIR™ FTIR Microscope as a solution that combines clear visual tools with precise infrared analysis and powerful software analytics. The microscope is positioned as an ideal tool to address the diverse challenges emerging in the pharmaceutical industry, catering to both novice and expert users.

Thermo Scientific™ Nicolet™ RaptIR™ FTIR Microscope

Thermo Fisher Scientific

The Thermo Scientific™ Nicolet™ RaptIR+™ FTIR Microscope offers precision and agility to help streamline sample analysis by quickly generating actionable results. Homing in on the intricacies of a sample to find the answer you need is often a lengthy and difficult process. Any amount of time saved while searching for the solution makes a world of difference in delivering results.

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Infrared / IR SpectroscopyInfrared (IR) spectroscopy measures the interaction of infrared light with a sample, including transmission, reflectance & absorbance, facilitating the identification of analytes. Equipment used for quantitative analysis includes Fourier-transform infrared (FTIR) spectrometers, infrared cameras, FTIR gas analyzers, as well as attenuated total reflectance (ATR) accessories and pellet or film presses. Find the best IR spectroscopy products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Near Infrared SpectroscopyNear-infrared (NIR) spectroscopy measures the interaction of near-infrared light with a sample, including transmission, reflectance and absorbance, facilitating the identification of analytes. Measurements can be conducted using a Fourier-transform near infrared (FT-NIR) spectrometer, while there are also UV-Vis- NIR spectrophotometers that measure a broader spectrum of wavelengths. Find the best NIR spectroscopy products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Quality ControlQuality control is needed in all production processes. Quality control is a monitoring procedure or set of procedures that are put in place to ensure that a manufactured product adheres to a defined set of quality criteria. Quality TestingQuality testing ensures that products meet required specifications and safety standards in various industries, including pharmaceuticals, food, and materials. It is essential for maintaining product quality and consumer safety. Explore quality testing tools in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.PharmaceuticalsPharmaceuticals are medicinal drugs used in healthcare to diagnose, prevent, cure and treat illnesses. Pharmaceuticals that are excreted after use appear in wastewater and can have detrimental effects on the environment.