ResourceSpectroscopy

Raman spectroscopy: Rapid QC of healthcare products

15 Jun 2020

The development of Raman spectroscopy has come a long way since its discovery in 1928. Its combination with optical microscopy in the latest, next-generation confocal Raman microscopes has enabled fast, non-destructive, non-invasive hyperspectral imaging of samples without the need for sample preparation in most cases.

In this application compendium, we look at some of the wide-ranging applications of Raman microscopy to address various formulation challenges encountered by the pharmaceutical and cosmetics industries. In particular, we consider HORIBA Scientific’s latest confocal Raman imaging microscope, the LabRAM Soleil™, designed to make Raman imaging faster and easier than ever before.

Download the free eBook to discover how Raman microscopy can yield information on molecular structures, crystal phases, polymorphisms and much more, as we cover:

  • Characterization of pharmaceuticals, including compound distribution, chemical homogeneity and more
  • Characterization of cosmetics for perfect formulations
  • Raman spectroscopy as an essential tool in pharma

XploRA - Raman microscopy

HORIBA Scientific

The XploRA™ is a new concept in Raman microscopy, bringing Raman chemical identification directly to your microscope. The XploRA can be coupled to both upright and inverted microscopes, allowing analysis of all sample types, ranging from semiconductors and nano-materials, through to biological cells and tissues. The system provides the established performance of HORIBA Scientific Raman microscopes at a surprising price. Combining microscopy and chemical analysis the XploRA™ retains the full functionality of your microscope coupled with high performance Raman spectroscopy. The concept of the XploRA™ is straightforward – a smarter microscopy. A compact, high performance Raman spectrometer is coupled to a research grade optical microscope (upright or inverted geometry), allowing both standard optical microscopy and detailed chemical analysis on a single system. The unique design ensures full capability of the optical microscope, and complete flexibility, full automation and true research performance of the Raman analyzer.

(9)

LA-960 Laser Particle Size Analyzer

HORIBA Scientific

The most high-end class accurate and reliable laser diffraction particle sizing instrument HORIBA Partica LA-950V2 has been upgraded to the LA-960. HORIBA particle sizing instrument recognized as its strong point of submicron range measurement capability and the new model includes these advantages with some new features. HORIBA’s experience in the use of data algorithms has evolved to meet the expectations of the customer demanding the highest accuracy and resolution.LA-960 Laser Particle Size Analyzer Features: The dynamic wide measurement range; 0.01- 5000 microns (up to 3000 microns for wet method) Guaranteed high data accuracy of ±0.6% ISO13320 compliance Traceability support Easy and functional screen layout method expert function generates appropriate measurement conditions and reviews each analysis Data correlation software available

(4)

Links

Tags

Raman SpectroscopyRaman spectroscopy is used to discern the vibrational and rotational states of molecules and hence the chemical composition of a sample by measuring the inelastic scattering of monochromatic light. Explore a range of Raman spectrometers, including handheld/portable Raman spectrometers for QC/QA labs and in situ spectrometers for processes. Conduct Raman imaging for microanalysis of mixed samples using a Raman microscope. Raman spectrographs are also available. Find the best Raman spectroscopy products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Molecular BiologyMolecular biology is the branch of biology that focuses on the molecular mechanisms that underlie cellular functions. It involves studying DNA, RNA, and proteins to understand gene expression, replication, and regulation. Molecular biology is fundamental to biotechnology, medicine, and genetic research. Explore molecular biology products in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.Quality ControlQuality control is needed in all production processes. Quality control is a monitoring procedure or set of procedures that are put in place to ensure that a manufactured product adheres to a defined set of quality criteria. PharmaceuticalsPharmaceuticals are medicinal drugs used in healthcare to diagnose, prevent, cure and treat illnesses. Pharmaceuticals that are excreted after use appear in wastewater and can have detrimental effects on the environment.