ResourceSpectroscopy
Quantitative analysis of designer benzodiazepines in urine by LC-MS/MS
15 Jun 2023In this poster, Phenomenex focuses on tracking designer benzodiazepine substances obtained illicitly. LC-MS/MS techniques are crucial for the proper identification and quantitation due to cross reactivity with benzodiazepine immunoassay kits. The study targets 14 compounds in urine using high-sensitivity fast LC analysis. A Kinetex™ Biphenyl LC column is used for chromatographic separation, coupled with a SCIEX® 4500 triple quad for MS/MS detection.
Related products
Request Quote for All Products
Links
Tags
LC-MSLC-MS (liquid chromatography-mass spectrometry) systems and equipment are used for separation and quantitative analysis of complex mixtures, combining liquid chromatography and mass spectrometry. Quantify proteins, contaminants, pesticides or screen for drug metabolites with a high level of sensitivity. LC-MS systems and equipment include reverse phase, normal phase and specialized columns integrated with various MS detectors such as time-of-flight (TOF), quadrupole, orbitrap or ion trap mass analyzers. LC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzer give greater sensitivity and resolving power to your analysis. Find the best LC-MS equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Drug TestingIt is essential to test the efficacy and toxicity of drugs at every stage of their development to ensure that a pharmaceutical product is fit for purpose and safe for use before reaching the stage of mass production and distribution.BenzodiazepinesUrineThe analysis of urine is important in medicinal, anti-doping, forensic and life sciences applications. The ability to evaluate what someone has ingested through their urine enables fast detection and diagnosis of certain illnesses.