ResourceSpectroscopy
Quantitative analysis and determination of molecular weight of siRNA type oligonucleotides by LCMS™-8060
5 Feb 2025Examine how precision mass spectrometry can be used for nucleic acid drug analysis, including siRNA, antisense, and aptamer types. Explore the capabilities of the Shimadzu LCMS-8060 triple quadrupole mass spectrometer for quantitative analysis and molecular weight determination, and learn how it ensures accurate characterization and monitoring of synthetic oligonucleotides in drug development.
Links
Tags
Mass SpectrometryMass spectrometry (MS) is a powerful analytical technique used to identify and quantify molecules based on the mass-to-charge ratio of gas-phase ions. It provides detailed information about the structure, composition, and properties of compounds and is widely used across fields such as environmental monitoring, materials science, drug discovery and development, food and beverage testing, and wider chemical research. Key MS techniques include tandem mass spectrometry (MS/MS), liquid chromatography–mass spectrometry (LS-MS) and inductively coupled plasma (ICP-MS). Choosing from these wide range of techniques and technologies can be a daunting task, so keep up to date with scientific applications, performance expectations, and customer reviews here all in one place. Visit our product directory to receive quotes direct from the manufacturer.