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Quantitation of Ethyl Glucuronide and Ethyl Sulfate in Urine using LC-MS/MS

4 Feb 2019

A short, robust quantitative method for the analysis of ethyl glucuronide (EtG) and ethyl sulfate (EtS) using a Nexera LC coupled to LCMS-8045 triple quadrupole mass spectrometer was developed.

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LC-MSLC-MS (liquid chromatography-mass spectrometry) systems and equipment are used for separation and quantitative analysis of complex mixtures, combining liquid chromatography and mass spectrometry. Quantify proteins, contaminants, pesticides or screen for drug metabolites with a high level of sensitivity. LC-MS systems and equipment include reverse phase, normal phase and specialized columns integrated with various MS detectors such as time-of-flight (TOF), quadrupole, orbitrap or ion trap mass analyzers. LC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzer give greater sensitivity and resolving power to your analysis. Find the best LC-MS equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Mass SpectrometryMass spectrometry (MS) is a powerful analytical technique used to identify and quantify molecules based on the mass-to-charge ratio of gas-phase ions. It provides detailed information about the structure, composition, and properties of compounds and is widely used across fields such as environmental monitoring, materials science, drug discovery and development, food and beverage testing, and wider chemical research. Key MS techniques include tandem mass spectrometry (MS/MS), liquid chromatography–mass spectrometry (LS-MS) and inductively coupled plasma (ICP-MS). Choosing from these wide range of techniques and technologies can be a daunting task, so keep up to date with scientific applications, performance expectations, and customer reviews here all in one place. Visit our product directory to receive quotes direct from the manufacturer. MetabolitesMetabolites are the intermediate and end products of metabolism. Analyzing metabolites offers insight into cellular processes and disease mechanisms and is critical in fields like pharmacology, toxicology, and diagnostics. Explore our peer-reviewed product directory to find the best tools for metabolite analysis, compare products, check reviews, and get pricing directly from manufacturers.Alcoholic BeveragesThe analysis of alcoholic beverages involves testing their composition, quality, and safety, including alcohol content, flavor compounds, and impurities. This is essential for quality control and regulatory compliance. Explore tools for alcoholic beverage testing in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.
Quantitation of Ethyl Glucuronide and Ethyl Sulfate in Urine using LC-MS/MS