ResourceSpectroscopy

Quantitation of 22 fentanyl analog compounds with a TSQ Altis MD mass spectrometer

10 Nov 2023

The rise in not only the abuse of prescription drugs, but also synthetic opioids, has created a demand for toxicology labs to test for fentanyl-related compounds, including fentanyl. In this application note from Thermo Fisher Scientific, explore a method for quantitation of the Traceable Opioid Material™ (TOM) kit compounds in urine that includes sample preparation by supported liquid extraction (SLE) and quantitation by selected reaction monitoring (SRM) on a Thermo Scientific™ TSQ Altis™ MD Triple Quadrupole mass spectrometer.

TSQ Altis™ MD Mass Spectrometer

Thermo Fisher Scientific

Develop in vitro diagnostic tests for demanding quantitative analyses leveraging the enhanced sensitivity and remarkable speed and robustness of the Thermo Scientific™ TSQ Altis™ MD Series Mass Spectrometer. The TSQ Altis MD Series mass spectrometer, a Class I medical device, offers superb analytical performance and features the maximum usability, sensitivity and robustness required for laboratory developed tests (LDTs) from clinical diagnostic laboratories.

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Mass SpectrometryMass spectrometry (MS) is a powerful analytical technique used to identify and quantify molecules based on the mass-to-charge ratio of gas-phase ions. It provides detailed information about the structure, composition, and properties of compounds and is widely used across fields such as environmental monitoring, materials science, drug discovery and development, food and beverage testing, and wider chemical research. Key MS techniques include tandem mass spectrometry (MS/MS), liquid chromatography–mass spectrometry (LS-MS) and inductively coupled plasma (ICP-MS). Choosing from these wide range of techniques and technologies can be a daunting task, so keep up to date with scientific applications, performance expectations, and customer reviews here all in one place. Visit our product directory to receive quotes direct from the manufacturer.
Quantitation of 22 fentanyl analog compounds with a TSQ Altis MD mass spectrometer