Quality analysis using the Agilent ProteoAnalyzer system and SDS-PAGE

29 Feb 2024

Quality control provides valuable information about the integrity of samples such as proteins before use in assays, experiments, or product release. In this application note, learn more about the Agilent ProteoAnalyzer system, a parallel capillary electrophoresis instrument that automates the capillary electrophoresis-sodium dodecyl sulfate (CE-SDS) analysis of reduced and non-reduced protein samples including monoclonal antibodies, biosimilars, crude lysates, and protein purification fractions. Able to separate 12 samples in as little as 30 minutes, this system is designed to eliminate the laborious process of SDS-PAGE gel preparation, staining/destaining, and analysis. Streamlined sample preparation and intuitive software simplifies protein analysis workflows, making it easier to analyze the size and purity of the protein of interest.

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Protein QuantificationThe detection and quantification of proteins in a sample is vital across life sciences, pharmaceutical research and clinical diagnostics, and a variety of equipment is available to scientists to simplify the workflow. Proteins of interest can be easily labeled and detected on light-based detection instruments. Immunoassay kits allow you to identify a specific protein of interest and protein detection beads or antibody microarrays allow you to identify multiple specific proteins at once. Protein interactions and enzyme activity can also be monitored with protein-protein interaction assays. Additionally, the biophysical characterization of proteins is made easy with biokinetic analyzers. Find the best protein detection and quantification products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Quality ControlQuality control is needed in all production processes. Quality control is a monitoring procedure or set of procedures that are put in place to ensure that a manufactured product adheres to a defined set of quality criteria.
Quality analysis using the Agilent ProteoAnalyzer system and SDS-PAGE