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Product brochure: RarePlex Developer Kits for Ventana

RareCyte, Inc
28 Jul 2022

In this product brochure, learn about Rareplex Developer Kits for Ventana. RarePlex Developer Kits enable the detection of up to two additional biomarkers of your choice in the 405 and 488 imaging channels to companion RarePlex CTC Panel Kits for circulating tumor cell (CTC) identification.

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RarePlex Panel Kits

RareCyte, Inc

The RarePlex Panel Kit product line includes immunofluorescence Panel Kits and Developer Kits for circulating tumor cell (CTC) characterization, including enumeration, and specific kits include additional biomarkers for in-depth phenotypic characterization. RarePlex Panel Kits are highly validated circulating tumor cell assays designed to work with the AccuCyte® Sample Preparation System, automated slide staining systems, and CyteFinder® Instruments. Developer Kits are single channel kits and enable you to keep up with the pace of discovery. In order to provide you with assay flexibility, Developer Kits were design to allow the addition of 1-2 biomarkers of your choice to a Panel Kit.

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Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.BiomarkersBiomarkers are biological markers which can be measured and evaluated to indicate a biological state. The use of biomarkers in research and diagnosis can indicate a normal or disease state or drug response of cells / tissues. Biomarkers include genetic markers, cell surface markers such as antigens, antibodies or receptors and secreted molecules such as cytokines. An assay system is required for identification of biomarkers. :Assay DevelopmentThe process of proving an assay to be sensitive with respect to the target is known as assay development. The assay should be able to characterize novel compounds and measure the potency of these compounds against a validated biological target.CTCsBiomarker DiscoveryClinical biomarkers refer to substances related to known medical conditions that can be accurately measured <i>in vitro</i>. Biomarkers can be used to diagnose presence of a disease and indicate disease severity. The discovery of new biomarkers is incredibly valuable in the field of diagnostics.

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