ResourceLife Sciences
Principle of mitochondrial toxicity assessment using Agilent Seahorse XF Solution
15 Mar 2023Agilent Seahorse XF analyzers are used to study cellular metabolism in a diverse array of research areas, including assessment of drug-induced mitochondrial toxicity. In this white paper, Agilent outlines the approach and design of the Agilent Seahorse XF Mito Tox assay solution for the detection of mitochondrial toxicity using standardized parameters.
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Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.MitochondriaToxicityToxicity is defined as the degree to which a substance can harm humans or animals. It is essential to study the toxicity of pharmaceutical products during the development process so that optimum dosage can be established for the administration of the drug.
