ResourceLife Sciences
Primary Epithelial Ovarian Cancer Cells form Spheroids when Cultured on Corning® Ultra-Low Attachment Surfaces
18 Mar 2014Epithelial ovarian cancer (EOC) does not follow a traditional metastatic route via the bloodstream; instead, its spread involves exfoliation of EOC cells from the primary tumor, aggregation into multicellular spheroids, and diffusion within the peritoneal cavity. This application note describes how Corning Ultra-Low Attachment tissue culture products are used for the generation of a model system that can recapitulate spheroids associated with EOC.
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Cell / Tissue CultureCell culture or tissue culture is used to study the biology of cells or tissues and to isolate cellular products in an environment which can be manipulated and well defined. Accurately control your culture environment with bioreactors or culture incubators, bind your cells to a surface or together with an extracellular matrix. Distinguish cell types with differential media or proliferate cells with certain characteristics using selective media. Enrich your media with supplements such as growth factors, sera and vitamins. Find the best cell and tissue culture products, kits and equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.Cancer ResearchAlthough cancer is often referred to as a single condition, it actually consists of more than 100 different diseases. Microscopy, mass spectrometry, high throughput sequencing and flow cytometry are some of the most common techniques employed in cancer research labs.Ovarian Cancer