ResourceLife Sciences
Porcine Cross Reactivity in Human Simoa™ Assays NSE, NF-light® , GFAP, and cTnI; a TBI Study
18 Jan 2019The Quanterix Simoa HD-1 Analyzer offers an unprecedented ability to measure low abundant brain injury proteins in human circulation. A Yorkshire swine experimental traumatic brain injury (TBI) model that is used to study novel neuroprotective therapies for TBI provides an excellent opportunity for studying the kinetics of blood biomarkers of brain injury. This study explored the potential porcine cross-reactivity in human assays for neuron-specific enoloase (NSE), Neurofilament light (NF-light), glial fibrillary acidic protein (GFAP), and cardiac Troponin I (cTnI).
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Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.TroponinNeurobiologyNeurobiology studies the biology of the nervous system, including the structure and function of neurons, glial cells, and their interactions. It is a key field in understanding neurological disorders such as Alzheimer�s, Parkinson�s, and schizophrenia. Research in neurobiology is essential for developing therapies for these conditions. Browse our peer-reviewed product directory to find the best neurobiology research tools, compare products, check reviews, and get pricing directly from manufacturers.