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Polymeric vs Silica Based Solid Phase Extraction Columns for the Analysis of Delta-9-THC and 11-nor-9-Carboxy-THC in Oral Fluid

UCT, Inc.
29 Dec 2014

Cannabis is the most widely used illegal substance in the world, where humans smoke or ingest it for its psychotropic effects. Analytical methods for quantifying cannabinoids and their metabolites exist for plasma, blood, urine, hair, sweat and oral fluid. This study explores the efficiency of polymeric versus silica based solid phase columns for the extraction of Delta-9-THC and its primary metabolite 11-nor-9-Carboxy-THC from oral fluid prepared using the Quantisal™ Synthetic Negative Oral Fluid diluted with extraction buffer.

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Positive Pressure Manifold

UCT, Inc.

Positive Pressure Manifold - A simple, robust way to quickly process up to 48 samples at one time. The Positive Pressure Manifold can accommodate a multitude of column sizes and provides even flow to each position. Positive Pressure Manifold Features: All 48 positions are individually regulated to provide even pressure to each column. There are four banks of 12 positions each. The user can control flow to each of the four banks. Capacity of 1 to 48 columns adaptable for size 1mL, 3mL, 6mL, 10mL or 15mL. Air Supply: N2 or compressed air regulated to 75 psi and filtered to 10μm. Dual pressure regulators allow users to set different pressures for extraction and column drying. Includes waste reservoir that drains automatically. Single switch raises and lowers the sample racks and creates an airtight seal.

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Clean Screen® XCEL Solid Phase Extraction Columns

UCT, Inc.

The Clean Screen® XCEL Solid Phase Extraction Columns are a line of sample prep phases designed to reduce the number of steps in the extraction, and therefore the amount of time and solvent necessary to complete the sample cleanup. Further advantages include reduced sample size and improved cleanliness and recovery. The Xcel I column will extract a wide array of basic drugs including benzodiazepines and opiates. The Xcel II column is designed solely for the extraction of the THC metabolite.

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Polymeric vs Silica Based Solid Phase Extraction Columns for the Analysis of Delta-9-THC and 11-nor-9-Carboxy-THC in Oral Fluid