ResourceLife Sciences
Pitched-Blade vs. Spin Filter vs. Packed-bed Basket: CHO Cell Culture Comparison
6 Feb 2014In this application note, the pitched-blade impeller, the spin filter impeller and the packed-bed basket impeller are discussed, highlighting the uses and advantages for each type. Examples of actual CHO cell cultures are given for each impeller type; showing the perfusion capability when using the spin filter or packedbed basket impeller and the resulting higher cell densities over the pitched-blade impeller.
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Cell / Tissue CultureCell culture or tissue culture is used to study the biology of cells or tissues and to isolate cellular products in an environment which can be manipulated and well defined. Accurately control your culture environment with bioreactors or culture incubators, bind your cells to a surface or together with an extracellular matrix. Distinguish cell types with differential media or proliferate cells with certain characteristics using selective media. Enrich your media with supplements such as growth factors, sera and vitamins. Find the best cell and tissue culture products, kits and equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Bioprocessing / FermentationBioprocessing is the use of biological materials to perform commercial, scientific or medical research processes. Biological materials used include cells, enzymes and organisms. Usually bioprocessing requires a batch or continuous bioreactor such as a fermentor or cell culture system. The advantages of using a reactor include high productivity, easy configuration, adjustable values and automation.