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Pioneering advanced nucleic acid analysis for gene and cell therapy development at TATAA Biocenter

Agilent Technologies
1 Jul 2025

Explore how the TATAA Biocenter, a specialized contract research organization (CRO) in Gothenburg, Sweden, uses the Agilent 5200 and 5300 Fragment Analyzer systems, featuring 12- and 96 channels, respectively, to meet the standards of high sensitivity, specificity, precision, and accuracy. The instruments also enable full sample traceability through integration with the lab’s LIMS system.

Discover how in addition to RNA QC for assay development and biomarker analysis, the Fragment Analyzer systems also play a key role in QC during NGS library preparation, as they are used to determine average fragment sizes, detect adapter-dimer artifacts, and identify over- or underamplification of the library.

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Fragment Analyzer Systems

Agilent Technologies

The Agilent Fragment Analyzer systems are fluorescence-based capillary electrophoresis instruments for the accurate sizing, quantification, and qualification of nucleic acids (DNA and RNA).

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Capillary ElectrophoresisCapillary electrophoresis (CE) is used to separate molecules based on charge, size and hydrophobicity. Pressure, voltage or a vacuum is used to introduce the sample to fused silica capillaries. Fluorescence, UV/Vis, UV or diode array detectors are used to visualize components. Types of CE systems include capillary electrochromatography (CEC), capillary zone electrophoresis and capillary gel electrophoresis. Find the best capillary electrophoresis equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Cell TherapyCell therapy involves using living cells to treat diseases, often by replacing damaged cells or stimulating regeneration. Stem cell therapy and CAR-T cell therapy are examples of cutting-edge treatments in regenerative medicine and cancer immunotherapy. Browse our peer-reviewed product directory to find the best cell therapy tools, compare products, check reviews, and get pricing directly from manufacturers.Gene TherapyGene therapy is a technique that modifies or replaces genes within an individual's cells to treat or prevent diseases. This approach holds potential for curing genetic disorders, cancers, and certain viral infections. Advances in gene editing technologies like CRISPR are driving the growth of gene therapy. Explore gene therapy tools and technologies in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.

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Pioneering advanced nucleic acid analysis for gene and cell therapy development at TATAA Biocenter