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PFAS Analysis in Aqueous Samples per EPA Draft Method 1633

Agilent Technologies
25 Sept 2022

This application note addresses PFAS testing in aqueous wastewater samples per the EPA draft method 1633 using Agilent Bond Elut PFAS WAX SPE cartridges. The instrumentation for analysis utilized the Agilent 1290 Infinity II liquid chromatograph (LC) system coupled to the Agilent 6470 triple quadrupole (TQ) mass spectrometer (LC/TQ). The study verified method performance in terms of analyte extraction recoveries, sensitivity (method detection limits), and reproducibility.

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Agilent Bond Elut PFAS WAX SPE Cartridges

Agilent Technologies

Worried about your sample preparation product meeting regulatory guidelines? Agilent Bond Elut PFAS WAX SPE cartridges are a cost-effective solution for PFAS analysis and were created to meet current regulation requirements. That means you can spend more time on the things that matter—like generating reliable results and increasing your lab’s revenue.

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Sample PreparationSample preparation can improve the quality and speed of separation techniques. Products to assist sample preparation include filtration equipment, evaporators, membranes and sieves.LC-MSLC-MS (liquid chromatography-mass spectrometry) systems and equipment are used for separation and quantitative analysis of complex mixtures, combining liquid chromatography and mass spectrometry. Quantify proteins, contaminants, pesticides or screen for drug metabolites with a high level of sensitivity. LC-MS systems and equipment include reverse phase, normal phase and specialized columns integrated with various MS detectors such as time-of-flight (TOF), quadrupole, orbitrap or ion trap mass analyzers. LC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzer give greater sensitivity and resolving power to your analysis. Find the best LC-MS equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Solid-Phase ExtractionSolid-phase extraction (SPE) is used for clean-up, extraction and concentration of semi-volatile or non-volatile analytes from complex mixtures including blood, urine and food samples. Multiple formats are available for conducting SPE, including prepacked SPE cartridges, disks and microplates, as well as SPE sorbent powders for manual packing. SPE systems can be used to automate the process and extract multiple samples at once. Solid-phase microextraction (SPME) and supported liquid extraction (SLE) products are also available in the same formats. Find the best SPE, SLE and SPME equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Water AnalysisAnalytical methods used to test the purity of drinking water include determining the level of contaminants abides to the level set by the Environmental Protection Agency (EPA).Environmental AnalysisEnvironmental analysis describes a variety of tests that determine the effect of chemicals, processes and particulates such as persistent organic pollutants (POPs) have on the environment.Solid Phase Extraction (SPE)Solid phase extraction (SPE) is a sample preparation technique used to separate and concentrate analytes from complex mixtures. It is widely used in environmental, pharmaceutical, and clinical analysis. SPE provides higher sensitivity and selectivity compared to traditional liquid-liquid extraction methods, making it essential for accurate and reproducible results. Explore SPE tools and systems in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.

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PFAS Analysis in Aqueous Samples per EPA Draft Method 1633