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Orion tissue investigation: Tonsil lymphoid hyperplasia

RareCyte, Inc
10 Nov 2022

Here, RareCyte presents its Orion tissue investigation into tonsil lymphoid hyperplasia.

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Orion Multiplex Imaging Instrument

RareCyte, Inc

The Orion Platform delivers spatial biology and cellular phenotyping at a speed and resolution needed for translation from research to the clinic. It utilizes single round immunofluorescence staining and imaging of standard FFPE or fresh frozen tissue to deliver subcellular quantitation of biomarker targets across a whole slide in only a few hours. Combining speed and resolution with the additional benefits of industry-standard H&E and IHC modes, comprehensive phenotypic profiling of patient cohorts can be generated for characterization of tissue architecture, tumor heterogeneity, and the immune response. Use your own antibodies, run panels from an extensive biomarker list, or engage RareCyte services for custom panels and programs.  

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AntibodiesAntibodies are used in techniques such as confocal and fluorescence microscopy, flow cytometry, ELISA, ELISPOT, immunohistochemistry, western blotting and immunopreciptation. Select specific antigen reactivity, high specific affinity, low non-specific binding, monoclonal or polyclonal, primary or secondary antibodies and associated conjugates such as an enzyme or dye for visualization.Cell / Tissue CultureCell culture or tissue culture is used to study the biology of cells or tissues and to isolate cellular products in an environment which can be manipulated and well defined. Accurately control your culture environment with bioreactors or culture incubators, bind your cells to a surface or together with an extracellular matrix. Distinguish cell types with differential media or proliferate cells with certain characteristics using selective media. Enrich your media with supplements such as growth factors, sera and vitamins. Find the best cell and tissue culture products, kits and equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.BiomarkersBiomarkers are biological markers which can be measured and evaluated to indicate a biological state. The use of biomarkers in research and diagnosis can indicate a normal or disease state or drug response of cells / tissues. Biomarkers include genetic markers, cell surface markers such as antigens, antibodies or receptors and secreted molecules such as cytokines. An assay system is required for identification of biomarkers. :Light MicroscopyLight microscopes or optical microscopes are used to visualize microscale objects under magnification, including cells, clinical specimens and materials. Lab equipment for light microscopy includes confocal microscopes, fluorescence microscopes, zoom and stereo microscopes. Microscope slides and imaging reagents are available for visualizing samples, as well as various microscope stages and incubators for large or temperature-sensitive samples. Find the best light microscopes in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Immunofluorescence

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Orion tissue investigation: Tonsil lymphoid hyperplasia