ResourceLife Sciences
N-Glycans profiling of MAbs EG2-hFc and Rituximab using the AdvanceBio Gly-X N-Glycan Prep with InstantPC kit
7 Apr 2022Download this application note to find a method for N-Glycan profiling. Protein glycosylation is one of the main sources of heterogeneity of therapeutic glycoproteins, with a potential impact on safety and efficacy, and is therefore considered a critical quality attribute (CQA). Therefore, this type of workflow holds great potential for reliable and reproducible sample preparation for high-throughput glycan profiling and quantitation. It can also easily be adapted to any analytical laboratory requirements.
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GlycobiologyGlycobiology encompasses research into the biological functions, synthesis and structures of glycans, including glycoproteins, glycolipids, proteoglycans and free oligosaccharides. Mass spectrometers and their software are commonly used in the study of glycobiology, along with structure predicting tools, chromatography and NMR.GlycansGlycosylation

