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MultiQuant™ Software 2.0 for Targeted Protein / Peptide Quantification

SCIEX
11 May 2017

Multiple Reaction Monitoring (MRM) is a mass spectrometry experiment that allows very sensitive and specific quantification of targeted analytes. MRM experiments require triple quadrupole systems. The QTRAP® system, which is a hybrid triple quadrupole linear ion trap instrument, can also perform these experiments because the Q3 can function as a linear ion trap or as a standard quadrupole. A key component of the MRM assay workflow is software processing, which is explained in this document.

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QTRAP 6500+ system

SCIEX

The QTRAP 6500+ system featuring the multi-component IonDrive technology and enhanced with an IonDrive high energy detector+ pushes the boundaries of LC-MS/MS quantitation farther than ever before. The revolutionary sensitivity, speed, and performance delivered through these technology enhancements are designed so you can see it all, from low mass to high mass compounds, in positive or negative polarity – in a single injection, with high sensitivity, reliability, and confidence. 

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ProteomicsProteomics is the systemic bioinformatics study of proteins and amino acids, including their structure, size, function and identification. Tools used in proteomics include chromatography, blotting and gels, protein arrays, mass spectrometry and ELISA and associated analysis software. Analyzers and proteomic systems should be sensitive, high resolution, fast and may be automated for high-throughput.Protein PurificationProtein purification is a vital step in drug discovery, therapeutics, biotech and life science research. The purification process typically involves subcellular or membrane protein extraction with cell lysis kits, separation of proteins from cell debris by filtration or spin columns, and the isolation of proteins of interest from other proteins and impurities with affinity purification (including fusion protein tags and antibody binding proteins A, G and L), immunoprecipitation or chromatographic methods, such as ion exchange, size exclusion and immobilized metal affinity chromatography. All purification methods come in multiple formats for your laboratory needs, including agarose or magnetic beads, resins, columns and filter plates. Find the best protein purification equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Software PlatformsSoftware platforms are useful for various stages of laboratory experiments from data collection to data storage and processing. For instance lab software is available for system control, data management, data analysis and qualification / validation.Protein BiologyProtein Quantification

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MultiQuant™ Software 2.0 for Targeted Protein / Peptide Quantification