ResourceSeparations
Monodisperse fully porous particle (MFPP) use for increasing resolution in liquid chromatography
2 Nov 2023In this application note, Mac-Mod discusses a way to increase the resolution in monodisperse fully porous particle (MFPP) when allied with a new range of stationary phase chemistry. This new discovery of combining monodisperse silica with new diverse stationary phase ligands will overcome the limitation of resolution when involving metabolites and isomeric species and potentially achieve greater selectivity and resolution between analytes. This new development will increase efficiency and create new selectivity options to develop more robust and reproducible methods to separate more complex sample mixtures.
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LC-MSLC-MS (liquid chromatography-mass spectrometry) systems and equipment are used for separation and quantitative analysis of complex mixtures, combining liquid chromatography and mass spectrometry. Quantify proteins, contaminants, pesticides or screen for drug metabolites with a high level of sensitivity. LC-MS systems and equipment include reverse phase, normal phase and specialized columns integrated with various MS detectors such as time-of-flight (TOF), quadrupole, orbitrap or ion trap mass analyzers. LC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzer give greater sensitivity and resolving power to your analysis. Find the best LC-MS equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Compound IdentificationChromatographyChromatography is a powerful technique used to separate and analyze components of mixtures based on their chemical properties. It is widely used in fields like biochemistry, pharmaceuticals, and environmental analysis. By exploiting differences in the interaction of substances with a stationary phase and a mobile phase, chromatography enables precise purification and quantification of compounds. Whether you're working with complex biological samples or industrial chemicals, chromatography is essential for obtaining high-quality results. Browse our peer-reviewed product directory to find the best chromatography systems, compare products, read customer reviews, and get pricing directly from manufacturers.