ResourceSpectroscopy
Monitoring a Chemical Reaction with Raman Spectroscopy and Multivariate Analysis
24 Jun 2015This application note describes a example where multivariate analytical methods were applied to Raman spectral data obtained during a chemical reaction in order to identify the presence of intermediates. Collecting spectral signatures during the reaction, then using principal component analysis (PCA) on the spectra, can reveal details about the reaction, including the presence of intermediates.
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Raman SpectroscopyRaman spectroscopy is used to discern the vibrational and rotational states of molecules and hence the chemical composition of a sample by measuring the inelastic scattering of monochromatic light. Explore a range of Raman spectrometers, including handheld/portable Raman spectrometers for QC/QA labs and in situ spectrometers for processes. Conduct Raman imaging for microanalysis of mixed samples using a Raman microscope. Raman spectrographs are also available. Find the best Raman spectroscopy products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Reaction MonitoringPharmaceuticalsPharmaceuticals are medicinal drugs used in healthcare to diagnose, prevent, cure and treat illnesses. Pharmaceuticals that are excreted after use appear in wastewater and can have detrimental effects on the environment.