Miniaturization of a Cell-based TNF-α AlphaLISA® Assay Using Echo® Liquid Handler and the PHERAstar FS

Screening for potential inhibitors of TNF-α production could lead to beneficial treatments for inflammatory diseases. Miniaturization for screening purposes presents an attractive scenario in which drug discovery can take place while saving on expenditure of target compounds and detection reagents. This application note describes the use of the PHERAstar FS from BMG LABTECH to detect an AlphaLISA® assay which has been miniaturized by the Echo® Liquid Handler from Labcyte.