Microstructure of skin cream using Cryo-planing and Cryo-FIB-SEM

28 Nov 2017

Soft materials containing water or other solvents, such as home and personal care products, are not high vacuum compatible. Therefore it is difficult to expose their microstructure. ZEISS demonstrates the use of cryo-SEM and cryo-FIB-SEM techniques in exposing the microstructure of a soft material, using face cream as an example. The study was carried out using a ZEISS FIB-SEM, equipped with a Gatan cryo preparation system (Alto 2500) and the Leica cryo-ultramicrotome Ultracut UCT EM FCS.

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Electron MicroscopyElectron microscopes (EM) are used to create high-resolution images of samples at the nanoscale by means of an accelerated beam of electrons as a source of illumination. Types of electron microscope include scanning electron microscopes (SEM), transmission electron microscopes (TEM), scanning transmission electron microscopes (STEM) and cryo-electron microscopes. Focused ion beam (FIB) microscopes are useful for modifying or milling a sample surface with nanometer precision, as well as imaging. Find the best electron microscopes in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.3D Imaging3D imaging technologies allow for the visualization and analysis of three-dimensional structures at high resolution. These systems are used in fields like molecular biology, material science, and medical diagnostics. 3D imaging can be applied to visualize cells, tissues, and organs, providing valuable insights into their structure and function. Browse our peer-reviewed product directory to find the best 3D imaging solutions, compare products, check reviews, and get pricing directly from manufacturers.SEMScanning Electron Microscopy (SEM) is a technique that uses a focused electron beam to scan a sample and create high-resolution images. It is widely used in materials science, nanotechnology, and biological research. Explore SEM systems in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.
Microstructure of skin cream using Cryo-planing and Cryo-FIB-SEM