ResourceSeparations

Measuring Volume Changes as a Result of Environment

Measuring Volume Changes as a Result of Environment

2 Dec 2015

As the demand for high throughput drug screening increases, modern drug discovery and research labs are utilizing complex automation systems to assist in screening novel drug candidates. 96 and 384 well plates are routinely used to achieve the necessary throughput required. As sample density increases, humans become more removed from the screening process and proper sample care can occasionally be overlooked. This application note describes a quick and easy way to understand the severity of absorption and evaporation on plates by monitoring small volume changes over the course of a normal day using the VMS (Volume Measuring System) from Artel.

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Sample PreparationSample preparation can improve the quality and speed of separation techniques. Products to assist sample preparation include filtration equipment, evaporators, membranes and sieves.Sample ManagementSample management systems include sample storage devices such as freezers and plate storers, sample environment enclosures and sample organization, retrieval and sorter systems. Useful system features include high-throughput, automation, robotic arms, automated liquid handling and associated database systems. Accessories in sample management include barcode scanners, heat sealers and tubes.Sample HandlingProper and careful handling of samples is important in scientific studies to ensure the integrity of specimens. This will prevent deterioration and cross contamination, and improve the accuracy of sample tracking procedures.Volume Verification SystemsHigh ThroughputHigh throughput experiments allow the simultaneous processing of several samples. This parallelization reduces the cost per experiment and increases reproducibility and output volume of data.ScreeningUsing robotics, data processing and control software, liquid handling devices and sensitive detectors, screening allows a researcher to quickly conduct millions of chemical, genetic or pharmacological tests.