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Low adsorption UPLC systems and columns based on MaxPeak High Performance Surfaces: The ACQUITY PREMIER solution

Waters
8 Feb 2021

Since the development of high-performance liquid chromatography (HPLC), stainless steel has been the preferred material of construction for chromatographs and columns. However, this can result in challenges arising, such as poor peak shapes or low recoveries for certain analytes.

In this white paper, Waters demonstrates how to overcome challenges in HPLC with a family of new technologies, named MaxPeak™ High performance Surfaces (HPS), and how this new technology has been applied to the components of a new UPLC system, named ACQUITY PREMIER, to help achieve optimal HPLC performance for metal-sensitive analytes.

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ACQUITY Premier System

Waters

Along with the reliability, ruggedness, high quality, and configuration flexibility you expect from the ACQUITY™ UPLC™ PLUS Series, the Waters™ ACQUITY Premier System delivers a step change in chromatographic performance, lab efficiency, and risk control.

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UHPLC and HPLCHigh performance liquid chromatography (HPLC) and ultra high performance liquid chromatography (UHPLC), also known as UPLC, are analytical techniques used to separate, identify and quantitate components of complex mixtures including biological samples such as proteins and lipids as well as chemical mixtures of pesticides, drugs and oils. Both techniques are liquid chromatographic methods but differ by operating pressures (HPLC < 6000 psi < UHPLC ). Components of HPLC and UHPLC systems include columns, detectors, pumps, autosamplers and column heaters. Explore a range of UHPLC and HPLC columns for your specific sample needs including reverse phase, normal phase, ion exchange, HILIC, ion exclusion and size exclusion columns. For more specialized HPLC, explore FPLC, countercurrent LC and simulated moving bed systems. Find the best UHPLC and HPLC equipment in our peer reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.ChromatographyChromatography is a powerful technique used to separate and analyze components of mixtures based on their chemical properties. It is widely used in fields like biochemistry, pharmaceuticals, and environmental analysis. By exploiting differences in the interaction of substances with a stationary phase and a mobile phase, chromatography enables precise purification and quantification of compounds. Whether you're working with complex biological samples or industrial chemicals, chromatography is essential for obtaining high-quality results. Browse our peer-reviewed product directory to find the best chromatography systems, compare products, read customer reviews, and get pricing directly from manufacturers.

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Low adsorption UPLC systems and columns based on MaxPeak High Performance Surfaces: The ACQUITY PREMIER solution