ResourceLife Sciences
Light Sheet Microscopy at the Harvard Center for Biological Imaging; Evaluation of the Lightsheet Z.1 Microscope from ZEISS
7 Jul 2015In the spring of 2013 the Harvard Center for Biological Imaging (HCBI) was able to demo, and eventually acquire, Lightsheet Z.1 microscope from ZEISS. The HCBI have now performed a number of long term embryonic development imaging experiments including imaging of zebrafish, fly, worm, cricket, and salamander embryos. Throughout these experiments, ZEISS Lightsheet Z.1 was employed to acquire both fast dynamics and long-term changes during development; this application note evaluates the use of ZEISS’ Lightsheet Z.1 in such experiments.
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Embryology / IVFEmbryology refers to the development of an embryo resulting from the fertilization of the ovum, to fetus stage. In vitro fertilization (IVF) refers to the fertilization of the egg outside of the human body, and is an important treatment for infertility.Light MicroscopyLight microscopes or optical microscopes are used to visualize microscale objects under magnification, including cells, clinical specimens and materials. Lab equipment for light microscopy includes confocal microscopes, fluorescence microscopes, zoom and stereo microscopes. Microscope slides and imaging reagents are available for visualizing samples, as well as various microscope stages and incubators for large or temperature-sensitive samples. Find the best light microscopes in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Fluorescence MicroscopyFluorescence microscopy has become an essential tool in biology, as well as in materials science. The application of many fluorochromes has made it possible to identify cells and sub-microscopic cellular components with a high degree of specificity. Using multiple fluorescence labels, different probes can simultaneously identify several target molecules.Research and DevelopmentEmbryonic Stem CellsEmbryo SurvivalMicroscopyMicroscopy is a technique used to observe small objects in detail, from cells to materials, using light or electron microscopes. It enables researchers to examine structures with high resolution, aiding in fields such as biology, medicine, and materials science. With advanced microscopy techniques, scientists can gain insights into cellular processes, tissue structures, and material properties. Explore the best microscopy solutions in our peer-reviewed product directory, compare products, read customer reviews, and get pricing directly from manufacturers.Developmental BiologyCell BiologyCell biology studies the structure, function, and behavior of cells. Understanding cellular processes is essential for research in areas such as cancer biology, stem cell research, and neurobiology. Techniques like flow cytometry, microscopy, and cell culture enable researchers to explore cellular mechanisms in detail. Browse our peer-reviewed product directory to find the best cell biology tools and equipment, compare products, check customer reviews, and get pricing directly from manufacturers.