ResourceSpectroscopy

<i>In-situ</i> Monitoring of a Moisture-Induced Polymorphic Transition using Raman Spectroscopy and Gravimetric Vapor Sorption

16 Sept 2014

This application note demonstrates that the combination of gravimetric vapor sorption with Raman spectroscopy allowed for the monitoring of the vapor-induced polymorphic transformation of D-mannitol polymorphs in real-time.

i-Raman ‒ High Resolution TE Cooled Raman Spectrometer

B&W Tek, Inc.

The i-Raman® is unique for its high resolution combined with field-portability, with performance comparable to large bench-top Raman systems and weighing less than 7lbs The i-Raman® is equipped with B&W Tek’s patented CleanLaze® technology for exceptional laser stabilization and narrow linewidth. Other features include a spectral resolution as fine as 3cm-1, wide Raman shift coverage up to 4000cm-1, and a TE cooled 2048 pixel CCD array. With a convenient fiber optic interface, it can collect data to within 65cm-1 of the Rayleigh Line.It is unique for its high resolution combined with field-portability, with performance comparable to large bench-top Raman systems and weighing less than 7 lbs. The system’s small footprint, lightweight design, and low power consumption provides research grade Raman capabilities anywhere!The i-Raman offers 532nm, 785nm, and 830nm excitation wavelength options. All i-Raman systems feature deep TE Cooling, allowing the maximum effective integration to be 4 minutes. This makes the i-Raman ideal for demanding applications involving low concentrations and weak Raman scatterers.i-Raman ‒ High Resolution TE Cooled Raman Spectrometer Features: Patented CleanLaze® Technology for Laser Stabilization 175cm-1 of the Rayleigh Line (65cm-1 Option Available) Fiber Optic Interface for Convenient Sampling Spectral Resolution of 3cm-1 Wide Raman Shift Coverage TE Cooled 2048 Pixel Array

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Raman SpectroscopyRaman spectroscopy is used to discern the vibrational and rotational states of molecules and hence the chemical composition of a sample by measuring the inelastic scattering of monochromatic light. Explore a range of Raman spectrometers, including handheld/portable Raman spectrometers for QC/QA labs and in situ spectrometers for processes. Conduct Raman imaging for microanalysis of mixed samples using a Raman microscope. Raman spectrographs are also available. Find the best Raman spectroscopy products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Moisture AnalysisMethod DevelopmentMethod development is the process of creating and optimizing experimental techniques and protocols to achieve reliable, reproducible results. This is essential in various fields, including pharmaceuticals, environmental science, and diagnostics. Browse our peer-reviewed product directory to find the best method development solutions, compare products, check reviews, and get pricing directly from manufacturers.
<i>In-situ</i> Monitoring of a Moisture-Induced Polymorphic Transition using Raman Spectroscopy and Gravimetric Vapor Sorption