ResourceLife Sciences
Label-free technologies for accurate determination of kinetics and affinity rate constants
15 Jun 2022Affinity constants are a key property for determining the degree of interactions between candidate therapeutic molecules and their target receptors. Download this application note to find out how the Octet® System can help advance your biotheraputic research.
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Octet® RH96 BLI System
Sartorius GroupUnrivaled performance with 2 minutes to quantitate 96 samples or 15 minutes to run 384 binding kinetics.
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ELISAEnzyme-linked immunosorbent assays (ELISA), also known as enzyme immunoassays (EIA), are used for the detection and quantification of proteins, peptides and antibodies in a sample. ELISA often comes in kit format, with pre-selected antibody pairs to detect specific proteins or biomarkers of diseases such as diabetes and obesity, or cardiovascular and neurological disorders. Detection is made possible with chemiluminescent, fluorescent or colorimetric substrates and detection instruments such as microplate / ELISA readers. Other kits available include: Enzyme-linked immunospot (ELISPOT) assays for the quantification of protein-producing cells and chemiluminescent immunoassays (CLIA) kits. Find the best ELISA kits and products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.InterferometryInterferometry is an investigative technique used to analyze the pattern of interference created during the superposition of 2 or more waves. An interferometer is used to produce 2 or more overlapping waves. The interferometer is comprised of 2 or more telescopes, a detector and a correlator. The interferometer detector may utilize homodyne or heterodyne detection of the interference pattern.Assay DevelopmentThe process of proving an assay to be sensitive with respect to the target is known as assay development. The assay should be able to characterize novel compounds and measure the potency of these compounds against a validated biological target.Cell Based AssaysCell-based assays use living cells to measure biological responses to various treatments or stimuli. They are essential for drug discovery, toxicology testing, and understanding cellular mechanisms. These assays are used to assess cell viability, proliferation, gene expression, and other cellular activities. Browse our peer-reviewed product directory to find the best cell-based assay tools and reagents, compare products, read customer reviews, and get pricing directly from manufacturers.