ResourceLife Sciences
IVT mRNA encapsulation efficiency assessment using Agilent Fragment Analyzer systems
2 Jul 2025Explore the Agilent Fragment Analyzer systems and discover how they can perform both quantitative and qualitative nucleic acid analysis using parallel capillary electrophoresis, and are routinely used in the characterization of in vitro transcribed (IVT) mRNA drug substance (DS) and drug product (DP). Critical quality attributes (CQAs) commonly assessed with the systems include integrity, size, and purity. The systems can also be used to streamline the IVT mRNA CQA workflow, consolidating essential tests for characterizing IVT mRNA onto one platform.
Related products
Request Quote for All Products
Fragment Analyzer Systems
Agilent TechnologiesThe Agilent Fragment Analyzer systems are fluorescence-based capillary electrophoresis instruments for the accurate sizing, quantification, and qualification of nucleic acids (DNA and RNA).
Links
Tags
Capillary ElectrophoresisCapillary electrophoresis (CE) is used to separate molecules based on charge, size and hydrophobicity. Pressure, voltage or a vacuum is used to introduce the sample to fused silica capillaries. Fluorescence, UV/Vis, UV or diode array detectors are used to visualize components. Types of CE systems include capillary electrochromatography (CEC), capillary zone electrophoresis and capillary gel electrophoresis. Find the best capillary electrophoresis equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Encapsulation