ResourceLife Sciences
Comprehensive isotope ratio analysis of amino acids using Orbitrap Exploris Isotope Solutions
5 Jun 2025This technical note highlights the use of Thermo Scientific™ Orbitrap Exploris™ Isotope Solutions for precise isotope ratio analysis of amino acids, focusing on glutamic acid as a model compound. Glutamate plays a key role in metabolism, neurotransmission, and nitrogen excretion. The advanced Orbitrap™ technology enables simultaneous carbon, nitrogen, oxygen, and hydrogen isotope ratio analysis from intact molecular ions by a single analysis, offering valuable insights into biochemical processes and metabolic pathways.
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Thermo Scientific™ Orbitrap Exploris™ Isotope Solutions
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Mass SpectrometryMass spectrometry (MS) is a powerful analytical technique used to identify and quantify molecules based on the mass-to-charge ratio of gas-phase ions. It provides detailed information about the structure, composition, and properties of compounds and is widely used across fields such as environmental monitoring, materials science, drug discovery and development, food and beverage testing, and wider chemical research. Key MS techniques include tandem mass spectrometry (MS/MS), liquid chromatography–mass spectrometry (LS-MS) and inductively coupled plasma (ICP-MS). Choosing from these wide range of techniques and technologies can be a daunting task, so keep up to date with scientific applications, performance expectations, and customer reviews here all in one place. Visit our product directory to receive quotes direct from the manufacturer.
Amino AcidsIsotope Ratio Mass SpectrometryElectrospray Ionization