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Integration of the Vi-CELL BLU Cell Viability Analyzer into the Sartorius Ambr 250 High Throughput

Beckman Coulter Life Sciences
26 Sept 2024

A Vi-CELL BLU cell viability analyzer integrated into a Sartorius Ambr® 250 High Throughput system leverages the strengths of both instruments and provides users with the advantages of automated cell culture handling and analysis. The combination of these technologies provides researchers and bioprocess engineers with many benefits, such as continuous monitoring and enhanced data analysis, while saving valuable time and resources. Automated cell culture analysis helps optimize workflows and could improve scalability. Explore the data from cultivations performed in a Sartorius Ambr® 250 High Throughput system which were sampled daily on an integrated Vi-CELL BLU analyzer to determine cell concentration and viability online. These results are compared with offline values.

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ambr® 250

Sartorius Group

ambr® 250 is a new bioreactor system for parallel fermentation or cell culture using 100-250mL single-use bioreactors controlled by an automated liquid handling platform.The new system, developed with two major industrial partners, builds on the original ambr® microscale technology developed by TAP Biosystems (now part of Sartorius Stedim Biotech).

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Cell / Tissue CultureCell culture or tissue culture is used to study the biology of cells or tissues and to isolate cellular products in an environment which can be manipulated and well defined. Accurately control your culture environment with bioreactors or culture incubators, bind your cells to a surface or together with an extracellular matrix. Distinguish cell types with differential media or proliferate cells with certain characteristics using selective media. Enrich your media with supplements such as growth factors, sera and vitamins. Find the best cell and tissue culture products, kits and equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Automation Supplies / AccessoriesAutomated accessories and consumables make lab processes fast, efficient and reliable. Useful automation accessories include microplate sealers, label printers and reagent reservoirs.Bioprocessing / FermentationBioprocessing is the use of biological materials to perform commercial, scientific or medical research processes. Biological materials used include cells, enzymes and organisms. Usually bioprocessing requires a batch or continuous bioreactor such as a fermentor or cell culture system. The advantages of using a reactor include high productivity, easy configuration, adjustable values and automation.Cell AnalysisThe analysis of cells allows researchers to understand the factors which contribute to cell health and function. These influencing processes can then be predicted and altered, leading to the development of medication and disease treatments.Cell ViabilityCell viability assays assess the health of cells and their ability to proliferate. These tests are crucial in drug development, toxicity testing, and cell-based research. Common methods for assessing viability include MTT, live/dead assays, and flow cytometry. Browse our peer-reviewed product directory to find the best tools for cell viability assays, compare products, check reviews, and get pricing directly from manufacturers.

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Integration of the Vi-CELL BLU Cell Viability Analyzer into the Sartorius Ambr 250 High Throughput