Integrating Automation and DOE to streamline and Accelerate Quality by Design Activities for Process Chemistry

18 Sept 2018

Getting drugs to market is hard. Modern drug development organizations face many business and environmental challenges. Billions of dollars are spent on new molecules or vaccine discoveries that can fail at any point in development, during the manufacturing process or in clinical trials. It is critical to design safe drug products and develop robust processes that minimize project risk as a candidate moves through development, out to the plant and into humans. In addition, in the eyes of the regulator, the application of Quality by Design (QbD) principals will soon become mandatory in drug submissions.

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Process ChemistryProcess chemistry is an important stage of drug development for scaling-up drug production or chemical synthesis reactions. It is useful for optimizing economical and efficient drug production. Process chemistry uses reactors and pump systems as well as reagents, standards and buffers.Software PlatformsSoftware platforms are useful for various stages of laboratory experiments from data collection to data storage and processing. For instance lab software is available for system control, data management, data analysis and qualification / validation.AutomationAutomation in laboratories and manufacturing processes enhances efficiency, precision, and scalability by reducing the need for manual intervention. It plays a critical role in improving productivity, minimizing human error, and accelerating workflows in fields like diagnostics, drug development, and industrial testing. Automation technologies include robotic systems, automated liquid handlers, and process control systems that streamline complex tasks and ensure consistent, reproducible results. Explore our peer-reviewed product directory to discover the best automation solutions, compare options, read user reviews, and get prices directly from manufacturers.Process OptimizationProcess optimization involves improving the efficiency, cost-effectiveness, and quality of processes in various industries, including manufacturing, pharmaceuticals, and biotechnology. Explore process optimization solutions in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.Compound ScreeningCompound screening is a method used to discover specific compounds that could be promising candidates for pharmaceutical use. This potential is identified when compounds interact with the target protein during screening and could therefore be carried forward in the drug development process.Drug DevelopmentDrug development refers to the process of bringing a new drug to market.
Integrating Automation and DOE to streamline and Accelerate Quality by Design Activities for Process Chemistry