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Increasing Spatial Resolution of Lipid Biomarker Analysis by LDI FTICR-MS

Bruker Daltonics
9 Aug 2015

The combination of temperature proxy potential of lipids in the sedimentological record with the high spatial resolution of laser desorption ionization (LDI) coupled to FT-ICR-MS can be used to produce estimates on sub-decadal to sub-annual scales and potentially provide crucial, previously hidden insights on the conditions of past climates and aid marine micro-organism knowledge. This scientific poster describes the use of a 12T solariX FTICR-MS coupled to a dual ion source with the Smartbeam II Laser for LDI FTICR-MS analysis of several cm-long sediment core segments.

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High-performance MALDI-TOF/TOF mass spectrometer with a unique combination of speed, sensitivity, and accuracy, providing advanced analytical capabilities for research, discovery, and routine applications.

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Mass SpectrometryMass spectrometry (MS) is a powerful analytical technique used to identify and quantify molecules based on the mass-to-charge ratio of gas-phase ions. It provides detailed information about the structure, composition, and properties of compounds and is widely used across fields such as environmental monitoring, materials science, drug discovery and development, food and beverage testing, and wider chemical research. Key MS techniques include tandem mass spectrometry (MS/MS), liquid chromatography–mass spectrometry (LS-MS) and inductively coupled plasma (ICP-MS). Choosing from these wide range of techniques and technologies can be a daunting task, so keep up to date with scientific applications, performance expectations, and customer reviews here all in one place. Visit our product directory to receive quotes direct from the manufacturer. Environmental Monitoring and TestingEnvironmental monitoring and testing uses handheld portable analyzers, kits, spectrometers or chromatography systems for air, water, soil, food and other sample testing. Useful features of analyzers such as BOD and COD include portability, easy calibration, automation and sensitivity.  Environmental test kits for pH, water, moisture, etc, should be accurate, sensitive, reliable, fast and easy to use.LipidsLipids are a diverse group of organic compounds that are insoluble in water, including fats, oils, and hormones. They are critical for cellular structure and energy storage. Explore lipid analysis tools in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.Biomarker DiscoveryClinical biomarkers refer to substances related to known medical conditions that can be accurately measured <i>in vitro</i>. Biomarkers can be used to diagnose presence of a disease and indicate disease severity. The discovery of new biomarkers is incredibly valuable in the field of diagnostics.Environmental AnalysisEnvironmental analysis describes a variety of tests that determine the effect of chemicals, processes and particulates such as persistent organic pollutants (POPs) have on the environment.

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