ResourceForensics
Improved Tools for Examining Low Copy Number (LCN) DNA Obtained from Challenged or Degraded Samples
27 Jul 2012This poster highlights several ways in which LCN typing can be improved upon using different approaches. These include: 1) improvements to the robustness of the amplification through the use of PCR enhancers; 2) increasing DNA recovery using pressure cycling technology (PCT), improved silica columns, or synchronous coefficient of drag alteration technology (SCODA); and 3) more efficiently reducing inhibition.
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DNA / RNA Extraction and PurificationPurified DNA and RNA are required for numerous downstream molecular biology applications. Consequently, the importance of high-quality DNA/RNA extraction and purification equipment cannot be underestimated. Many purification kits are available and are typically optimized for nucleic acid type and source, including plasmid DNA, genomic DNA, mRNA, RNA and viral nucleic acid purification kits. Automated extraction and purification of nucleic acids can be implemented with magnetic bead separator instruments or high-throughput purification workstations. Find the best DNA/RNA extraction and purification equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.DNA SequencingDNA sequencing, such as sanger sequencing, is a biological technique that determines the precise order of nucleotide bases in a fragment or template of DNA. DNA sequencers and genetic analyzers are based on capillary electrophoresis, where labeled DNA fragments are electrophoretically separated by size as they migrate through a polymer. Find the best DNA sequencing products, including DNA sequencing kits, genomic libraries and genetic identity kits in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.LCNLow Copy Number