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Improved Clean Up and Recovery of Pharmaceutical Compounds From Plasma
3 Feb 2017Diclofenac is a post-operative pain reliever that has also been shown to diminish the formation of the pro-inflammatory hormones. This application note describes the use of two popular extraction methods, solid phase extraction (SPE) and liquid-liquid extraction (LLE), for the isolation of diclofenac from plasma using Strata-X SPE. This article demonstrates the capability of Strata-X SPE to retain hydrophobic neutral compounds as well as acidic and basic compounds.
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Strata-X Polymeric SPE
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Solid-Phase ExtractionSolid-phase extraction (SPE) is used for clean-up, extraction and concentration of semi-volatile or non-volatile analytes from complex mixtures including blood, urine and food samples. Multiple formats are available for conducting SPE, including prepacked SPE cartridges, disks and microplates, as well as SPE sorbent powders for manual packing. SPE systems can be used to automate the process and extract multiple samples at once. Solid-phase microextraction (SPME) and supported liquid extraction (SLE) products are also available in the same formats. Find the best SPE, SLE and SPME equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Solid Phase Extraction (SPE)Solid phase extraction (SPE) is a sample preparation technique used to separate and concentrate analytes from complex mixtures. It is widely used in environmental, pharmaceutical, and clinical analysis. SPE provides higher sensitivity and selectivity compared to traditional liquid-liquid extraction methods, making it essential for accurate and reproducible results. Explore SPE tools and systems in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.Solvent Extraction