Immune system humanized mouse models for efficacy testing

23 Oct 2024

Immune system humanized mice are rapidly becoming the gold-standard for testing immuno-therapeutics. Their ability to provide functional human immune cells and human tumors, provide drug developers with an invaluable opportunity to predict the clinical performance of their lead compounds. Jackson Laboratory's variants are available in several configurations such as, naïve immunodeficient hosts, immune humanized, and/or engrafted with a human tumor. Discover how you can benefit from routinely tested, proof-of-concept, IND-enabled efficacy and safety tested mouse models.

JAX® Mice and Services

The Jackson Laboratory

Take advantage of our large inventories of common inbred strains and the convenience of having your breeding and drug efficacy needs met by the leading experts in mouse modeling.

(0)

Links

Tags

Animal ModelsThe use of non-human animals in experiments or behavorial observations. The research is conducted inside universities, medical schools, pharmaceutical companies, farms, defence establishments, and commercial facilities that provide animal-testing services to industry. It includes pure research such as genetics, developmental biology, behavioral studies, as well as applied research such as pharmaceutical testing in pre-clinical, before human, studies. Clinical TrialsClinical Trials, an essential part of drug discovery process, assess the safety and effectiveness of a new medication or device in the pharmaceutical industry. Clinical Trials are a phased process (Phase 0, Phase I, Phase II, Phase III and Phase IV) which begins after initial preclinical testing.Cellular PathologyCellular Pathology deals with the microscopic analysis of tissue samples and cells. Sample preparation and processing includes fixation, staining, sectioning and slide mounting, using equipment such microtomes and cryostats. In choosing immunohistochemistry and immunocytochemistry kits, consider chromogens, staining method, antibodies, microscopes and imaging.Immunological Research
Immune system humanized mouse models for efficacy testing