Imaging Chemiluminescence by Scanning Using the C-DiGit® Chemiluminescent Western Blot Scanner

The C-DiGit® Chemiluminescent Western Blot Scanner is a digital replacement for film, combining the sensitivity of film with the convenience and flexibility of a CCD imager. To achieve this breakthrough at an affordable price, LI-COR implemented a new imaging approach that was previously considered impossible: line-read scanning of chemiluminescent signals. Film-quality Western images are digitally captured in as little as 6 minutes, and no changes are generally required in detection protocols or reagents. The low-noise sensor array and short optical working distance maximize the efficiency of light collection and enable rapid line-scan imaging. The sensitivity, dynamic range, and affordability of the C-DiGit Blot Scanner make it a true digital replacement for film in Western blotting.