Identify stable biologic candidates during cell line development with Aura PTx
24 Apr 2025This application note showcases how Aura PTx enables early characterization of antibody stability during CHO cell line development. By utilizing high-throughput, low-volume subvisible particle analysis, Aura PTx assesses the physical stability of secreted antibodies in unfiltered samples. The method supports informed candidate selection and enhances biologic developability from the start, addressing challenges posed by complex biologic modalities and high titer demands.
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Aura PTx
Halo LabsAura® PTx gets you to your best formulation faster! Backgrounded Imaging (BMI) technology to give you accurate count, size, and morphology information about particles in your sample. Couple that with Fluorescence Membrane Microscopy (FMM), which gives you definitive ID of protein aggregates and an easy way to monitor polysorbate degradation.