High-throughput ToxTracker ACE genotoxicity assay on the MACSQuant X flow cytometer

2 Oct 2019

In this application note, Miltenyi Biotec presents a rapid and simple assay for the collection of genotoxicity information . The combination of the ToxTracker ACE assay and MACSQuant X flow cytometer is designed to enable the generation of high-quality, reliable results that are required for compound screening and safety studies in the field of drug discovery and development.

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Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.GenotoxicityToxicityToxicity is defined as the degree to which a substance can harm humans or animals. It is essential to study the toxicity of pharmaceutical products during the development process so that optimum dosage can be established for the administration of the drug.MultiplexingMultiplexing refers to the ability to measure multiple targets or analytes simultaneously in a single experiment. This technique is valuable for high-throughput screening, diagnostics, and complex assays, as it increases efficiency and data quality. Browse our peer-reviewed product directory to find the best multiplexing products, compare tools, check reviews, and get pricing directly from manufacturers.
High-throughput ToxTracker ACE genotoxicity assay on the MACSQuant X flow cytometer