ResourceLife Sciences
High-throughput single cell screening for cancer research
28 May 2025
Dora Wells
Clinical Content Editor
Single cell analysis is reshaping the landscape of life science research—revealing rare cell types, exposing hidden heterogeneity, and delivering actionable insights into disease mechanisms that were once out of reach.
In this free eBook, discover how Scale Biosciences is leading the next generation of single cell innovations. Learn how cutting-edge, scalable platforms are transforming RNA sequencing, CRISPR screening, and DNA methylation studies—at a fraction of the cost and complexity.
You'll learn how to:
- Scale your single cell research
- Achieve ultra-high throughput RNA sequencing
- Profile CRISPR knockout experiments at scale
- Optimize DNA methylation analysis
- Combine single cell methylation libraries with targeted enrichment
Who is this eBook for?
- Cancer biologists exploring tumor heterogeneity
- Genomics and epigenetics researchers
- Functional genomics scientists running CRISPR or perturbation screens
- Bioinformaticians and computational biologists seeking scalable data generation
- Translational researchers working on drug discovery pipelines
- Core facility scientists building single cell workflows for broad use
- Academic labs transitioning from bulk to single cell approaches
- Pharma and biotech scientists advancing precision medicine
Related products
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Single Cell RNA Sequencing Kit
Scale BiosciencesMassively parallel barcoding technology enables you to easily scale up to 500,000 cells in a single experiment.
Single Cell CRISPR Guide Enrichment Kit
Scale BiosciencesAmplify a CRISPR guide sequence derived from a CROP-style vector alongside your standard RNA Sequencing Library.
Single Cell Methylation Kit
Scale BiosciencesScale Bio’s Single Cell Methylation Kit revolutionizes epigenetics research as the first commercial solution for detecting single cell DNA methylation states.
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High-Throughput ScreeningHigh-throughput screening (HTS) is an automated drug discovery technique for identification of active compounds against a compound library. Use HTS readers and integrated assay preparation / analysis workstations to screen your compounds. Identify active compounds against various HTS libraries, including membranes, proteins and peptides and HTS cell lines. Find the best high-throughput screening products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.DNA SequencingDNA sequencing, such as sanger sequencing, is a biological technique that determines the precise order of nucleotide bases in a fragment or template of DNA. DNA sequencers and genetic analyzers are based on capillary electrophoresis, where labeled DNA fragments are electrophoretically separated by size as they migrate through a polymer. Find the best DNA sequencing products, including DNA sequencing kits, genomic libraries and genetic identity kits in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Next Generation SequencingNext-generation sequencing (NGS), also known as whole-genome sequencing, high-throughput sequencing and massive parallel sequencing, produces and analyses thousands to millions of nucleotide sequences at once. Sequencing systems operate via varying technologies depending on the manufacturer, including sequencing by synthesis, ligation, pyrosequencing, ion semiconductor and single-molecule real-time sequencing. For NGS, library preparation is paramount to successful sequencing. In this section, explore a range of library preparation kits, from targeted, amplicon-based or hybridization-based kits including epigenomic, transcriptomic and genomic workflows to fragmentation kits. Find the best next-generation sequencing products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Epigenetic AnalysisEpigenetic analysis products are used to study heritable phenotype changes that do not alter the DNA sequence, such as DNA modifications affecting gene activity. Determine whether genes have been methylated with DNA methylation quantification kits or methylation microarrays. Assess epigenetic regulation with histone modification kits or ChIP-on-chip microarrays. Kits are also available for bisulfite conversion and amplification of your samples, as well as epigenomic library preparation kits for next-generation sequencing (NGS). Find the best epigenetic products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.CRISPRCRISPR technology enables precise editing of genes, allowing scientists to modify DNA at specific locations. This revolutionary tool is used in genetic research, drug development, and gene therapy. CRISPR has applications in agriculture, disease treatment, and creating genetically modified organisms (GMOs). Explore CRISPR solutions in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.Genome SequencingGenome sequencing involves determining the complete DNA sequence of an organism's genome. It provides crucial information about genetic variations, mutations, and diseases. Advances in sequencing technologies, such as next-generation sequencing (NGS), have accelerated research in genomics, diagnostics, and personalized medicine. Explore genome sequencing tools in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.Cancer GenomeRNA sequencing