ResourceLife Sciences
High-speed full-well imaging for assessing cell positivity
23 Aug 2024Measuring cell positivity is essential in high content imaging. With broad applications from measuring gene induction to viral infectivity and clonal analysis, assays scoring cells as positive or negative based on fluorescent intensity levels are used in virtually every high content screening lab. This method explores live/dead staining, a common cell positivity assay that quantifies dead cells based on a dye that selectively infiltrates permeable cells but not healthy cells.
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Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.Cell ViabilityCell viability assays assess the health of cells and their ability to proliferate. These tests are crucial in drug development, toxicity testing, and cell-based research. Common methods for assessing viability include MTT, live/dead assays, and flow cytometry. Browse our peer-reviewed product directory to find the best tools for cell viability assays, compare products, check reviews, and get pricing directly from manufacturers.Cell ImagingCell imaging can be achieved using a number of techniques including confocal microscopy, transmission electron microscopy, atomic force microscopy, and light sheet microscopy.