ResourceSpectroscopy

High-performance ion mobility spectrometry: Applications in pharmaceutical manufacturing and development

28 Jul 2020

High performance ion mobility spectrometry (HPIMS) combines the speed, sensitivity, and robustness of ion mobility with laboratory-grade resolution, specificity and repeatability. It separates molecules by size and shape on a timescale of milliseconds, allowing for rapid compositional analysis and the differentiating between coeluting compounds and isomers. In this application note, Excellims presents applications for both IMS and IMS-MS.

Links

Tags

Mass SpectrometryMass spectrometry (MS) is a powerful analytical technique used to identify and quantify molecules based on the mass-to-charge ratio of gas-phase ions. It provides detailed information about the structure, composition, and properties of compounds and is widely used across fields such as environmental monitoring, materials science, drug discovery and development, food and beverage testing, and wider chemical research. Key MS techniques include tandem mass spectrometry (MS/MS), liquid chromatography–mass spectrometry (LS-MS) and inductively coupled plasma (ICP-MS). Choosing from these wide range of techniques and technologies can be a daunting task, so keep up to date with scientific applications, performance expectations, and customer reviews here all in one place. Visit our product directory to receive quotes direct from the manufacturer. Ion Mobility SpectrometryPharmaceuticalsPharmaceuticals are medicinal drugs used in healthcare to diagnose, prevent, cure and treat illnesses. Pharmaceuticals that are excreted after use appear in wastewater and can have detrimental effects on the environment.
High-performance ion mobility spectrometry: Applications in pharmaceutical manufacturing and development