Heat Activation of TRPV1 on Nanion's Patchliner®

7 Feb 2011

This application note presents data collected on the 4-channel Patchliner ® with temperature control showing the potential use of the Patchliner® to record capsaicin and heat activation of TRPV1 channels and subsequent block by ruthenium red (RR).

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ElectrophysiologyElectrophysiology is the study of biological voltage changes, from a single ion channel through to a whole organ scale. Voltages can be measured using patch clamping, automated workstations, electrophysiology rigs or cell based assays. Specific cell lines, manipulators and microinjectors are also available for electrophysiology research.
Heat Activation of TRPV1 on Nanion's Patchliner®